Bob Bishop



Personalien und Diagnosen

Personalien

Sichtbarer Name: Bob Bishop
Land: Great Britain
Bundesland/Kanton: England
Geburtsjahr: 1945
Alter: 78
Beruf: IT Consultant
Hobbys: Singing, Geology, Hiking
Meine Homepage: www.crozierchorale.com

Daten bei Erstdiagnose

Datum: 06.09.2009
Alter bei Diagnose: 64
PSA: 7.20
Biopsiert? Ja
TUR-P? Nein
Gleason Score: 4 + 4 = 8
TNM-Diagnose: T3a N0 M0
Bemerkung: Bone scan clear

Maximal gemessenes Prostatavolumen

Datum:
PSA:
Volumen in ml oder cm³:

Postoperative pathologische Daten

Datum: 19.11.2009
Gleason Score: 4 + 3 = 7b
pTNM-Befund: T3a N0 M0
Schnittränder:
p-L-V-P-G-Befunde:
Siehe Bericht vom:

Prostatakrebs - Behandlungen

** PSA-Wert zu Beginn der Behandlung
von bis PSA** Art Klinik Ort
19.11.09 7.30 Offene OP Holly House London
10.03.10 07.05.10 3.00 IMRT London Oncology Centre London
01.04.11 01.10.11 10.20 intermittierende HB Shrubberies Medical Centre London
01.10.11 15.10.12 0.11 Active Surveillance The London Clinic London
15.10.12 8.00 HB 1-fach Shrubberies Medical Centre London



Medikamente

NEM = Nahrungsergänzungsmittel
von bis Medikament + NEM Menge / Zeiteinheit
17.03.10 Casodex
01.04.10 01.10.10 Triptorelin Monthly/3-Monthly
Menge pro T/W/M/J etc.


PSA-Verlauf    ng/ml    logarithmisch

PSA-Verlauf    ng/ml    linear

PSA-Verdoppelungszeiten in Jahren

Verdoppelungszeit ist zur Vorperiode gestiegen.
Verdoppelungszeit ist zur Vorperiode gesunken.
* Berechnet auf 1, 2, 4 und 8 Perioden rückwärts.

Grenzwert = 3 Jahre


Berechnung der Verdoppelungszeit in Tagen

Verdoppelungszeit in Jahren:
Verdoppelungszeit in Tagen:
Datum PSA 1* 2* 4* 8*
05.06.09 7.10
07.07.09 6.90 --
08.09.09 7.30 2.12 6.49
12.12.09 2.36 -- --
09.02.10 3.00 0.47 -- --
06.09.10 3.60 2.18 1.21 --
06.12.10 5.24 0.46 1.02 --
07.03.11 10.20 0.26 0.33 0.58
07.06.11 0.43 -- -- -- --
05.09.11 0.11 -- -- -- --
01.10.11 0.13 0.30 -- -- --
08.12.11 0.30 0.15 0.18 -- --
20.02.12 1.00 0.12 0.13 0.58 --
12.04.12 2.50 0.11 0.11 0.13 --
15.06.12 5.60 0.15 0.13 0.13 15.92
10.08.12 7.10 0.45 0.22 0.15 --
17.09.12 8.00 0.60 0.50 0.19 0.30
14.11.12 1.10 -- -- -- 0.36
07.01.13 0.30 -- -- -- 1.05
23.04.13 0.10 -- -- -- --
10.08.13 0.75 0.10 0.45 -- --
01.11.13 3.80 0.10 0.10 0.54 2.58
26.11.13 6.60 0.09 0.09 0.20 6.11
29.01.14 11.90 0.21 0.15 0.11 1.97
23.04.14 2.20 -- -- 0.45 --
Datum PSA 1* 2* 4* 8*
08.08.14 0.36 -- -- -- --
14.10.14 1.01 0.12 -- -- 1.01
13.01.15 7.85 0.08 0.10 -- 0.27
13.02.15 14.40 0.10 0.09 0.30 0.35
01.05.15 2.91 -- -- 0.24 --
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           

Mein Bericht

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Datum Δ 

letzter PSA vom

Erfahrungsberichte

       
06.12.2010 5.24 06.12.10
Suspicions were raised originally by a raised PSA from a routine blood test in Summer 2009. After three months it was still up so I went for a biopsy which confirmed the presence of cancer. The bone scan was clear so on the recommendation of the urologist I had a radical prostatectomy in November 2009 which went well.

However, my PSA was still 2.36 so we went for EBRT (External Beam Radiation Treatment) as well. I am more or less fully continent but can't manage enough of an erection yet for proper sex. Otherwise I am fine but my PSA is still rising - 3.36 in September 2010 and 5.24 in December. This suggests that they will probably start hormone treatment in the Autumn some time.
       
06.04.2011 10.20 07.03.11
When my PSA was tested again in early March it had nearly doubled, from 5.24 to 10.3 in three months. This came as quite a shock. The oncologist was prepared to wait another three months before starting ADT but after thinking about it for a couple of days I was not prepared to wait. I felt as if I was on a runaway train accelerating rapidly downhill.

I researched the possibilities and was quite keen to try a triple androgen blockade but my oncologist persuaded me to go with what seems to be the standard treatment here, i.e. four weeks of Casodex and monthly injections of Zoladex starting after two weeks.

When I arrived for my first injection at my GP practice I discovered they had ordered Degarelix [aka Firmagon] instead. This gets injected into the buttock instead of the stomach. I hardly felt the injection.

That was nearly three weeks ago and I haven't noticed any side effects to speak of. Yesterday I felt really weary for no apparent reason and rather down but that may not be the ADT. I'm sure it's very easy to imagine things.

On the brighter side I can now get quite a decent erection. It doesn't last very well but it is good enough for penetration - the first since my operation. I suspect this is likely to be a very temporary improvement but it did wonders for my morale.
       
06.06.2011 10.20 07.03.11
I have now been on ADT with Triptorelin (Decapeptyl) [aka Trelstar] for four months and it seems to be working. Using Triptorelin was a new departure for my GP practice but the administration is much easier than previous ADT treatments. The injection goes into the buttock and is (usually) painless. There are 1 month, 3 month and 6 month versions.

So far the side effects have been minimal. My sex drive is definitely reduced but not totally absent and with Cialis I can get an erection. Hot flashes are quite frequent but not a big deal - it feels as if I'm blushing when I'm not.

The big news is that my PSA is down from 10.3 to 0.43
       
09.12.2012 1.10 14.11.12
By October 2011 my PSA was down to 0.13 and I decided to come off the ADT and watch progress. Over the next twelve months my PSA rose quite quickly to 5.6 doubling every six weeks or so and then the increase slowed down. No-one could explain why this was the case. I decided it was time to return to ADT and had a bone scan. My PSA decreased quickly again to 1.1 in two months with testosterone reduced to a very low level. The bone scan revealed a problem with vertebra T10 as well as with one rib which had also showed up on a previous test just before I started RT. There is considerable doubt about whether either of these are actually signs of cancer but discussions are continuing about this. After recent doubts expressed about intermittent ADT I have decided to have continuous ADT for the time being.
I have been taking a variety of supplements for some time. Currently these are (daily):
Lecithin (1200 mg)
Curcumin (Turmeric) (500 mg)
Fish Oil (1000 mg)
Vitamin D3 (2000 units)
Resveratrol (250 mg)
Pomegranate extract (250 mg)
I also eat a lot of tomatoes, cranberries and other fruit and veg.
Little evidence any of these help except that my Vitamin D level is rising - it was previously at the bottom end of the normal range.

       
11.11.2014 1.01 14.10.14
Since my prostatectomy I have had recurring stricture of the urethra and it has taken several cystoscopic interventions to stabilise this. Unfortunately, although I was almost fully continent soon after the operation, these repeated interventions have worsened the situation considerably to the extent that I needed to use a bag. I was referred to Professor Mundy at the The London Hospital. When his underlings tried to do an assessment which involved a catheter they could not insert it. I was about to go to the States to visit my daughter and he advised an indwelling catheter in case I get problems on the trip. That was so uncomfortable I came home a week early. In November 2014 I had an Artificial Urinary Sphincter fitted. This has been very successful although I still need one pad a day. My wife and I are going to the USA and New Zealand for three months this Autumn so - fingers crossed!
       
17.06.2015 2.91 01.05.15
I have now been on intermittent ADT with triptorelin since April 2011. The routine currently is to have a 6-month shot of Triptorelin and then, provided the PSA drops below 1, which it always has so far, to wait until the PSA gets back into double figures. Once the PSA starts to rise it doubles in a month to a month and a half. I'm now on my 4th cycle and my consultant is confident the treatment will remain effective for at least another couple of years. I now take a daily statin (Atorvastatin) which, according to latest research, has some benefit. In this last cycle there have been no side effects from the ADT at all. I now have a dog and we walk at least 3 miles a day together at a pretty brisk pace. This has helped keep my weight down and my general health up.
       

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